RISK OF TUBERCULOSIS IN CHILDBEARING-AGE WOMEN WITH DIABETIC MELLITUS AND MALNUTRITION IN EASTERN INDONESIA BASED ON THE 2018 NATIONAL BASIC HEALTH SURVEY

Abstract

Diabetes mellitus has previously been identified as a comorbidity among tuberculosis patients due to a weak immune system. Malnutrition, on the other hand, is still a public health issue and a risk factor for tuberculosis. This study aimed to investigate the risk of tuberculosis in childbearing-age women who have diabetes and malnutrition in East Indonesia. The secondary data of this study were from the 2018 National Large Cross-Sectional Survey. To describe national representatives, a multistage sample was used as a sampling method. However, this analysis was limited to the East Indonesia Region with 13 provinces prevalence of malnutrition is highly found there. The logistic regression in complex samples was used to examine the risk of tuberculosis in diabetic patients and was adjusted for nutrition status and other factors. The samples of this study were 82,252 participants. The prevalence of malnutrition was determined to be undernutrition (17.8%), overweight (12.1%), and 20.9% of obese status. The prevalence of tuberculosis is 0.1% while the prevalence of diabetes mellitus diagnosed by doctors is 1.1%. Results of this study shows that determinant of tuberculosis are being diabetic patients (adjusted odds ratio (aOR) = 7.45; 95% confidence interval (CI): 3.80-14.60, p<0.001), chronic energy malnutrition (CEM) (aOR = 3.30; 95% CI: 2.20-4.90, p<0.001), age group 20-35 (aOR = 1.75; 95% CI: 0.90-3.10, p=0.002), age group 36-59 (aOR = 2.70; 95% CI: 1.60-4.50, p<0.001). We concluded that patients with diabetes are the most vulnerable to has tuberculosis.