Double blinded peer review process is conducted.  Briefly, the Journal Editor determines and approaches the reviewers whose expertise matches with the topic or scope of the manuscript.  Number of reviewers depends on the complexity of the manuscript.  Generally, in addition to a content expert who will oversee the scientific merit of the manuscript, another reviewer will determine the appropriateness of research design together with the statistical analysis.  Reviewers should declare their conflict of interest, if any, before accepting the invitation.