RELATIONSHIP BETWEEN COVID-19 VACCINATION AND COVID-19 DISEASE IN BOGOR CITY, INDONESIA

Authors

  • Nikson Sitorus
  • Vissia Ardiyani
  • Alfons M Letelay
  • Ning Sulistiyowati
  • Noer Endah Pracoyo
  • Mugi Wahidin

Keywords:

vaccination, COVID-19, Bogor

Abstract

Indonesia and the world experienced a rapid increase in coronavirus disease 2019 (COVID-19) cases by the Delta variant in 2021. Clinical trials have reported positive results of vaccines on shielding COVID-19 infection.  However, their effectiveness to prevent infection in the Indonesian population is limited.  Using a cross-sectional design, we aimed to seek a relationship between COVID-19 vaccination and COVID-19 disease during the pandemic in 2021 in Bogor City, Indonesia.  This study was an extension of the ongoing prospective cohort study in five urban villages in Bogor Tengah District, Bogor City.  In total, 722 respondents were recruited in 2021 and divided into two groups according to the types of COVID-19 tests. Covariates included COVID-19 vaccination status, COVID-19 test result status, and demographic variables.  Simple and multiple logistic regressions were performed.  We found that there were 20.6% of respondents exposed to COVID-19.  About two-thirds (69.9%) of respondents had obtained their second or third vaccinations while those who received the first vaccination were 14%.  Despite the high coverage of vaccination, 15.7% were still unvaccinated. Among the vaccinated respondents, 67.7% got the Sinovac vaccine.  In a multivariate analysis, we found that respondents who were vaccinated once had a risk of being exposed to COVID-19 by 2.2 times (95% confidence interval (CI): 1.354-3.613; p=0.002) compared to those who were vaccinated ≥2 times after controlling for education and work.  In summary, full vaccinations effectively protect people from COVID-19 disease.

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Published

2023-12-18 — Updated on 2023-12-18

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