FLUCONAZOLE AND FIRE NEEDLE THERAPY TO  TREAT CHROMOBLASTOMYCOSIS: A CASE REPORT AND LITERATURE REVIEW

Authors

  • Xiaoqin Liu Department of Infectious Disease, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
  • Yan Li
  • Yujie Bao
  • Qiong Huang
  • Wenhuan Guo
  • Shu Chen
  • Jie Xu

Keywords:

chromoblastomycosis, fluconazole, fire needle, adjuvant therapy

Abstract

Chromoblastomycosis (CBM), a chronic subcutaneous infection caused by traumatic inoculation of a dematiaceous fungus, may be associated with severe morbidity and is difficult to treat.  We report here the case of CBM in a 67-year-old male who presented to our institution with a 4-month history of skin lesions on the dorsum of the right hand.  He was treated with a combination of fluconazole and fire needle therapy (acupuncture using red-hot needles) to eradicate lesions.  The lesions resolved after 2 months of treatment and he had no further relapses.  We also review the treatment of CBM in the literature.  Further studies are needed to determine if this combination of fluconazole combined with fire needle therapy may be a possible treatment option for CBM.

Author Biographies

  • Xiaoqin Liu, Department of Infectious Disease, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine

    Department of Infectious Diseases, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine

  • Yan Li

    The second author. Xiaoqin Liu and Yan Li contributed equally to this manuscript.

    Department of Traditional Chinese Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine

  • Yujie Bao

    Department of Infectious Diseases, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine

  • Wenhuan Guo

    Department of Pathology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine

  • Shu Chen

    Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University

  • Jie Xu

    Department of Infectious Diseases, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine

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Published

2024-01-08

How to Cite

FLUCONAZOLE AND FIRE NEEDLE THERAPY TO  TREAT CHROMOBLASTOMYCOSIS: A CASE REPORT AND LITERATURE REVIEW. (2024). The Southeast Asian Journal of Tropical Medicine and Public Health, 54(6), 392-402. https://journal.seameotropmednetwork.org/index.php/jtropmed/article/view/932

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