ANALYSIS OF EXTERNAL RISK FACTORS AND CHOLINESTERASE ENZYME LEVELS IN FEMALE FARMERS IN BREBES REGENCY

Abstract

One of the indicators that can assess the degree of public health is the maternal mortality rate (MMR). One of the causes of maternal death is abortion. World Health Organization (WHO) estimates that around 4.2 million abortions occur annually in Southeast Asia and it is estimated that abortion cases in Indonesia reach 2.3 million incidents annually. This study aimed to analyze external risk factors and levels of cholinesterase enzymes with the incidence of spontaneous abortion in women of childbearing age shallot farmers in Brebes. This type of research is an analytical observational study with a case-control design. The results showed that there was no significant relationship between workload (p=0.195), pesticide exposure level (p=0.364) and levels of the enzyme cholinesterase (p=0.830) with the prevalence of spontaneous abortion in farmers in Brebes; there is a significant relationship between using personal protective equipment (PPE) (p=0.0001) and antenatal care (ANC) quality (p=0.001) with the incidence of spontaneous abortion in farmers in Brebes and there is a significant relationship between the use of PPE (odds ratio (OR) = 6.606; 95% confidence interval (CI): 1.857-23.502, p=0.004) and ANC qualities (OR = 0.175; 95% CI: 0.065-0.471, p=0.001) with the prevalence of spontaneous abortus in childbearing age farmers in Brebes Regency.